AUTHORS
José Javier González-Cervantes
Antonio Ruíz-Hontangas
KEY WORDS
Risk factors, Gadolinium, Cancer patients, Magnetic resonance imaging, Renal function.
ABSTRACT
Goal: To describe the risk factors of the administration of Gadolinium for magnetic resonance imaging (MRI) in cancer patients with some type of renal alteration, detected in the interview held with nurses.
Method. Retrospective descriptive observational case study. The sample consisted of 218 subjects admitted to the Fundación Instituto Valenciano de Oncología hospital (FIVO in Spanish) in Valencia, Spain. Subjects with an estimated glomerular filtration rate (eGFR) >30ml/min/1,73m2 were selected, divided into two subgroups: stable patients (maintained or improved) and non-stable patients (worsening). The study period was from March to May 2020. The modified European Society of Urogenital Radiology (ESUR) questionnaire was used. Data was coded in a Microsoft Excel Redmond® database and analysed with R v3.4.0® software via the Rstudio® integrated development environment. 95% CI for p-value <0.05.
Results. In the sample analysed, the administration of Gadolinium for MRI in cancer patients did not lead to the relevant deterioration of the renal function. There was evidence of a relationship between the worsening of eGFR with increasing age and blood pressure. The female sex was found to be protective.
Conclusions. The administration of gadolinium-based contrast media for MRI in cancer patients was not associated with increased renal damage. Questionnaires applied by nurses can obtain relevant information for detecting risk factors not necessarily associated with cancer. Questionnaires applied by nurses can obtain relevant information for detecting risk factors not necessarily associated with cancer. The risk factors associated with eGFR were age, high blood pressure and sex.